Weibliche Geschlechtshormone

 

THE PRIMARY ORGANS AND STRUCTURES IN THE REPRODUCTIVE SYSTEM

  • The uterus is a pear-shaped organ located between the bladder and lower intestine. It consists of two parts, the body and the cervix. 
  • When a woman is not pregnant the body of the uterus is about the size of a fist, with its walls collapsed and flattened against each other. During pregnancy the walls of the uterus are pushed apart as the fetus grows. 
  • The cervix is the lower portion of the uterus. It has a canal opening into the vagina with an opening called the os, which allows menstrual blood to flow out of the uterus into the vagina. 
  • Leading off each side of the body of the uterus are two tubes known as the fallopian tubes. Near the end of each tube is an ovary. 
  • Ovaries are egg-producing organs that hold between 200,000 and 400,000 follicles (from folliculus, meaning "sack" in Latin). These cellular sacks contain the materials needed to produce ripened eggs, or ova. 
  • The inner lining of the uterus is called the endometrium, and during pregnancy it thickens and becomes enriched with blood vessels to house and support the growing fetus. If pregnancy does not occur, the endometrium is shed as part of the menstrual flow. Menstrual flow also consists of blood and mucus from the cervix and vagina.

REPRODUCTIVE HORMONES.

The hypothalamus (an area in the brain) and the pituitary gland regulate the reproductive hormones. 

The pituitary gland is often referred to as the master gland because of its important role in many vital functions, many of which require hormones. 

In women, six key hormones serve as chemical messengers that regulate the reproductive system: 

  • The hypothalamus first releases the gonadotropin-releasing hormone (GnRH). 
  • This chemical, in turn, stimulates the pituitary gland to produce follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
  • Estrogen, progesterone, and the male hormone testosterone are secreted by the ovaries at the command of FSH and LH and complete the hormonal group necessary for reproductive health.


OVULATION. 

The process leading to fertility is very intricate. It depends on the healthy interaction of two sets of organs and hormone systems in both the male and female. In addition, reproduction is limited by the phases of female fertility. Nevertheless, this astonishing process results in conception within a year for about 80% of couples. Only 15% conceive within a month of their first attempts, however, and about 60% succeed after six months. 

A woman's ability to produce children occurs after she enters puberty and begins to menstruate. 

The process to conception is complex: 

  • With the start of each menstrual cycle, follicle-stimulating hormone (FSH) stimulates several follicles to mature over a two-week period until their eggs nearly triple in size. 
  • Only one follicle becomes dominant, however, during a cycle. 
  • FSH signals this dominant follicle to produce estrogen, which enters the bloodstream and reaches the uterus. 
  • There, estrogen stimulates the cells in the uterine lining to reproduce, therefore thickening the walls. 
  • Estrogen levels reach their peak around the 14th day of the cycle (counting days beginning with the first day of a period). 
  • At that time, they trigger a surge of luteinizing hormone (LH).


LH serves two important roles: 

  • First, the LH surge around the 14th cycle day stimulates ovulation. It does this by causing the dominant follicle to burst and release its egg into one of the two fallopian tubes. Once in the fallopian tube, the egg is in place for fertilization. 
  • Next, LH causes the ruptured follicle to develop into the corpus luteum. The corpus luteum provides a source of estrogen and progesterone during pregnancy.

FERTILIZATION.

The so-called "fertile window" is six days long and starts five days before ovulation and ends the day of ovulation. 
Fertilization occurs as follows: 

  • The sperm can survive for up to three days once it enters the fallopian tube. 
  • The egg survives 12 to 24 hours unless it is fertilized by a sperm. 
  • If the egg is fertilized, about two to four days later it moves from the fallopian tube into the uterus where it is implanted in the uterine lining and begins its nine-month incubation. 
  • The placenta forms at the site of the implantation. The placenta is a thick blanket of blood vessels that nourishes the fertilized egg as it develops. 
  • The corpus luteum (the yellow tissue formed from the ruptured follicle) continues to produce estrogen and progesterone during pregnancy.



  • If the egg is not fertilized, the corpus luteum degenerates into a form called the corpus albicans, and estrogen and progesterone levels drop. 
  • Finally, the endometrial lining sloughs off and is shed during menstruation.